Publications

Selected publications

Slieker RC, Roost MS, van Iperen L, Suchiman HE, Tobi EW, Carlotti F, de Koning EJ, Slagboom PE, Heijmans BT*, Chuva de Sousa Lopes SM* (2015). DNA Methylation Landscapes of Human Fetal Development. Plos Genetics e1005583

Roost MS, van Iperen L, Ariyurek Y, Buermans HP, Arindrarto W, Devalla HD, Passier R, Mummery CL, Carlotti F, de Koning EJ, van Zwet EW, Goeman JJ, Chuva de Sousa Lopes SM (2015). KeyGenes, a tool to probe tissue differentiation using a human fetal transcriptional atlas. Stem Cell Reports 4:1112-24

Takasato M, Er PX, Chiu HS, Maier B, Baillie GJ, Ferguson C, Parton RG, Wolvetang EJ, Roost MS, Chuva de Sousa Lopes SM, Little MH (2015). Kidney organoids from human iPS cells contain multiple lineages and model human nephrogenesis. Nature 526:564-568

Duggal G, Warrier S, Ghimire S, Broekaert D, Van der Jeught M, Lierman S, Deroo T, Peelman L, Van Soom A, Cornelissen R, Menten B, Mestdagh P, Vandesompele J, Roost M, Slieker RC, Heijmans BT, Deforce D, De Sutter P, De Sousa Lopes SC*, Heindryckx B* (2015). Alternative routes to induce naïve pluripotency in human embryonic stem cells. Stem Cells 33:2686-2698

O’Leary T, Heindryckx B, Lierman S, van Bruggen D, Goeman JJ, Vandewoestyne M, Deforce D, Chuva de Sousa Lopes SM*, De Sutter P* (2012). Tracking the progression of the human inner cell mass during embryonic stem cell derivation. Nature Biotechnology 30: 778-782

Hayashi K*, Chuva de Sousa Lopes SM*, Tang F, Surani MA (2008). Dynamic equilibrium and heterogeneity of mouse pluripotent stem cells with distinct functional and epigenetic states. Cell Stem Cell 3:391-401

Chuva de Sousa Lopes SM, Hayashi K, Shovlin T, Mifsud W, Surani MA, McLaren A (2008). X chromosome activity in mouse XX primordial germ cells. PLoS Genetics 4:e30

Cree, LM, Samuels DC, Chuva de Sousa Lopes SM, Rajasimha HK, Wonnapinij P, Mann JR, Dahl HHM, Chinnery P (2008). A reduction of mitochondrial DNA molecules during embryogenesis explains the rapid segregation of genotypes. Nature Genetics 40:249-254

Brons IG, Smithers LE, Trotter MW, Rugg-Gunn P, Sun B, Chuva de Sousa Lopes SM, Howlett SK, Clarkson A, Ahrlund-Richter L, Pedersen RA, Vallier L (2007). Derivation of pluripotent epiblast stem cells from mammalian embryos. Nature 448:191-5

Hayashi K, Chuva de Sousa Lopes SM, Surani MA (2007). Germ cell specification in mice. Science 316:394-6