2016 – present

2018

Loomans CJM, Williams Giuliani N, Balak J, Ringnalda F, van Gurp L, Huch M, Boj SF, Sato T, Kester L, de Sousa Lopes SMC, Roost MS, Bonner-Weir S, Engelse MA, Rabelink TJ, Heimberg H, Vries RGJ, van Oudenaarden A, Carlotti F, Clevers H, de Koning EJP (2018). Expansion of adult human pancreatic tissue yields organoids harboring progenitor cells with endocrine differentiation potential. Stem Cell Reports 10:712-724

Gomes Fernandes M, He N, Wang F, Van Iperen L, Eguizabal C, Matorras R, Roelen BAJ, Chuva De Sousa Lopes SM (2018). Human-specific subcellular compartmentalization of P-element induced wimpy testis-like (PIWIL) granules during germ cell development and spermatogenesis. Hum Reprod 33:258-269

 

2017

Roost MS, Slieker RC, Bialecka M, van Iperen L, Gomes Fernandes MM, He N, Suchiman HED, Szuhai K, Carlotti F, de Koning EJP, Mummery CL, Heijmans BT, Chuva de Sousa Lopes SM (2017). DNA methylation and transcriptional trajectories during human development and reprogramming of isogenic pluripotent stem cells. Nat Commun 8:908

He N, Lim SJ, Moreira de Mello JC, Navarro I, Bialecka M, Salvatori DCF, van der Westerlaken LAJ, Pereira LV, Chuva de Sousa Lopes SM (2017). At term, XmO and XpO mouse placentas show differences in glucose metabolism in the trophectoderm-derived outer zone. Front Cell Dev Biol 5:63

Geens M, Chuva De Sousa Lopes SM (2017). X chromosome inactivation in human pluripotent stem cells as a model for human development: back to the drawing board? Hum Reprod Update 23:520-532

Warrier S, Van der Jeught M, Duggal G, Tilleman L, Sutherland E, Taelman J, Popovic M, Lierman S, Chuva De Sousa Lopes S, Van Soom A, Peelman L, Van Nieuwerburgh F, De Coninck DIM, Menten B, Mestdagh P, Van de Sompele J, Deforce D, De Sutter P, Heindryckx B (2017). Direct comparison of distinct naive pluripotent states in human embryonic stem cells. Nat Commun 8:15055

Lo Nigro A, de Jaime-Soguero A, Khoueiry R, Cho DS, Ferlazzo GM, Perini I, Abon Escalona V, Lopez Aranguren X, Chuva de Sousa Lopes SM, Koh KP, Conaldi PG, Hu WS, Zwijsen A, Lluis F, Verfaillie CM (2017). PDGFRα+ cells in embryonic stem cell cultures represent the In vitro equivalent of the pre-implantation primitive endoderm precursors. Stem Cell Reports 8:318-333

He N, van Iperen L, de Jong D, Szuhai K, Helmerhorst FM, van der Westerlaken LA, Chuva de Sousa Lopes SM (2017). Human extravillous trophoblasts penetrate decidual veins and lymphatics before remodeling spiral arteries during early pregnancy. PLoS One 12:e0169849

 

2016

Beets K, Staring MW, Criem N, Maas E, Schellinx N, de Sousa Lopes SM, Umans L, Zwijsen A (2016). BMP-SMAD signalling output is highly regionalized in cardiovascular and lymphatic endothelial networks. BMC Dev Biol 16:34

Schmitz F, Kooy-Winkelaar Y, Wiekmeijer AS, Brugman MH, Mearin ML, Mulder C, Chuva de Sousa Lopes S, Mummery CL, Staal FJ, van Bergen J, Koning F (2016). The composition and differentiation potential of the duodenal intraepithelial innate lymphocyte compartment is altered in coeliac disease. Gut 16:1269-1278

Bertocchini F, Chuva de Sousa Lopes SM (2016). Germline development in amniotes: A paradigm shift in primordial germ cell specification. Bioessays 38:791-800

Crisan M, Solaimani Kartalaei P, Neagu A, Karkanpouna S, Yamada-Inagawa T, Purini C, Vink CS, van der Linden R, van Ijcken W, Chuva de Sousa Lopes SM, Monteiro R, Mummery C, Dzierzak E (2016). BMP and hedgehog regulate distinct AGM hematopoietic stem cells ex vivo. Stem Cell Rep 6:383-95

Alves da Silva AF, Machado FB, Pavarino ÉC, Biselli-Périco JM, Zampieri BL, da Silva Francisco Junior R, Mozer Rodrigues PT, Terra Machado D, Santos-Rebouças CB, Gomes Fernandes M, Chuva de Sousa Lopes SM, Lopes Rios ÁF, Medina-Acosta E (2016). Trisomy 21 alters DNA methylation in parent-of-origin-dependent and -independent manners. PLoS One 11:e0154108

Villacorte M, Delmarcelle AS, Lernoux M, Bouquet M, Lemoine P, Bolsée J, Umans L, de Sousa Lopes SC, Van Der Smissen P, Sasaki T, Bommer G, Henriet P, Refetoff S, Lemaigre FP, Zwijsen A, Courtoy PJ, Pierreux CE (2016). Thyroid follicle development requires Smad1/Smad5- and endothelial-dependent basement membrane assembly. Development 143:1958-1970

Heeren AM, He N, de Souza AF, Goercharn-Ramlal A, van Iperen L, Roost MS, Gomes Fernandes MM, van der Westerlaken LA, Chuva de Sousa Lopes SM (2016). On the development of extragonadal and gonadal human germ cells. Biol Open 5:185-94

Gomes Fernandes M, Dries R, Roost MS, Semrau S, de Melo Bernardo A, Davis RP, Ramakrishnan R, Szuhai K, Maas E, Umans L, Abon Escalona V, Salvatori D, Deforce D, Van Criekinge W, Huylebroeck D, Mummery C, Zwijsen A, Chuva de Sousa Lopes SM (2016). BMP-SMAD signaling regulates lineage priming, but is dispensable for self-renewal in mouse embryonic stem cells. Stem Cell Rep 6:85-94

Orlova VV, Chuva de Sousa Lopes S, Valdimarsdottir G (2016). BMP-SMAD signaling: From pluripotent stem cells to cardiovascular commitment. Cytokine Growth Factor Rev 27:55-63